Scientist – Senior Scientist

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel immunological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes. aTyr is focused on the therapeutic translation of the Resokine pathway, comprised of extracellular proteins derived from the histidyl tRNA synthetase gene family. ATYR1923 is a clinical-stage product candidate, based on the Resokine pathway, which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in interstitial lung diseases and other immune-mediated diseases.   aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

aTyr Pharma is seeking an outstanding individual to join our Immunology Team. The Scientist/Senior Scientist will play an integral part in the development and characterization of novel immunomodulatory therapeutic candidates for the treatment of cancer and other inflammatory diseases. The ideal candidate will be a highly motivated independent individual who leads from the bench and enjoys having broad responsibilities and opportunities.

Primary Responsibilities

  • Design and execute MOA studies using methods such as multi-color flow cytometry, gene expression analysis techniques, MSD and other immunological assays
  • Design, develop, execute and analyze experiments to optimize processes for T cell expansion and immunological cell-based assays
  • Independently troubleshoot technical issues and develop optimized processes and assays for critical tasks
  • Work together with other departments within the company as well as with external collaborators
  • Be an active participant in internal and external meetings
  • Supervise research associate(s)
  • Contribute to a dynamic, exciting culture that embraces team work and innovation

Skills

  • Ability to independently design, plan, execute and interpret experiments
  • Hands-on experience and troubleshooting proficiency with immune cell isolation from peripheral blood and leukopak, cell expansion, and cell based immunoassays
  • Demonstrated experience with immunological assays to assess and characterize T cell function such as cytokine secretion, differentiation, activation, cytotoxicity and proliferation and suppression assay
  • Broad expertise in cellular immunology, tumor immunology, molecular biology, and flow cytometry
  • Expertise with multi-color flow cytometry (immune cell profiling) and flow data analysis is required, cell sorting experience a plus

Attributes

  • Proven track record of success through publications and presentations is required
  • Excellent organizational and planning skills
  • Excellent interpersonal, oral and written communication skills are essential in this collaborative environment

Experience

  • PhD with postdoc experience in human T cell biology and immunology (0-5 years’ industry experience)
  • Strong background in T cell biology and immunology is required, with background in oncology a plus

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.  aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job (#153SP) to jobs@atyrpharma.com.  aTyr Pharma, Inc. is an EEO employer.