Associate Director/Director Upstream Process Development

Associate Director/Director Upstream Process Development

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel immunological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

Position Summary

This position within the Process Sciences group is for an Associate Director/Director, Upstream to lead technology transfer and manufacturing activities at contract manufacturing organizations, and participate in strategic CMC planning and messaging to program teams and Executive Leadership. The candidate will collaborate with Quality, Clinical, and Research functional areas to help advance clinical and pre-clinical programs. The role also requires working closely with Analytical / Formulation and Downstream team members and provide technical guidance for internal upstream protein production operations in a mammalian cell culture lab, and contribute to the development and execution of mammalian cell culture and microbial fermentation processes.

The specific responsibilities include:

  • Developing/directing robust, scalable, well characterized and cost-effective upstream processes for the biologics pipeline

  • Process scale-up, facility fit analysis, optimization studies and successful process transfer

  • Ensure timely GMP manufacture with adherence to Quality Management Systems

  • Technical management of development and manufacturing operations at Contract Development and Manufacturing Organization (CDMOs)

  • Lead process characterization/validation studies (including scale-down models and design of experiment approach to identify critical process parameters) and process validation, including review of development, process characterization and validation protocols and reports

  • Serve as subject matter expert and provide technical expertise to process related trouble-shooting, and Quality support leveraging industry-standard root cause analysis methodologies.

  • Communicate clearly with program stakeholders, technical staff and CDMO partners

  • Ensure high quality source documentation to support global regulatory filings, including writing/reviewing)

Requirements

  • A Master’s or Ph.D. degree (Ph.D. preferred) in Biochemistry, Chemical/Biochemical Engineering, Chemistry, Biological Sciences or other relevant science or engineering field, with at least 10+ years of relevant industrial experience

  • Strong background and subject matter expertise in upstream unit operations including cell line development, fed-batch and perfusion cultures, bioreactor operations, impact of process conditions on product quality, scale-up and large scale manufacturing of recombinant proteins and antibodies

  • Late stage upstream development and contract manufacturing technical management experience

  • Demonstrated large scale mammalian cell culture-based bioprocess, technology transfer and manufacturing experience

  • Experience in upstream process development/manufacturing from microbial systems is also highly desirable

  • Knowledge of cGMP and regulatory requirements related to biologics manufacturing and controls, including authoring relevant CMC sections of IND/BLA filings, is highly desirable

  • Familiarity with statistical software, e.g. JMP is preferred

  • Extremely detail-oriented, thorough, and diligent in experimental design, data analysis and review

  • High level of motivation, initiative and creativity

  • Excellent organizational skills and ability to execute on multiple projects in parallel

  • Excellent written, verbal and presentation communication skills

  • Comfortable working in a high impact, fast-paced and lean biotech start-up environment. Ability to learn and act on dynamic information at a rapid pace.

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job 171DL to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

Scientific Intern, Translational Sciences

Scientific Intern, Translational Sciences

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel immunological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

Job Overview

The successful candidate will work on a variety tasks and learn what it is like to work in a biotech laboratory environment in a world-class organization. Tasks will include general laboratory duties such as labelling tubes, organizing, and restocking supplies; as well as performing more specialized experimental procedures. Experimental procedures will involve hands-on work with animal models, sample preparation as well as tissue culture. Successful candidate will be given the opportunity to join educational company meetings and events, attend scientific talks given by external experts, observe scientific experiments and learn a great deal. This is a paid internship up to 15 hours per week during school and more hours on summer break as the schedule allows.

Required background:

Must be currently enrolled in a life sciences major at an accredited university at the sophomore or junior level. Must have a strong academic background and a strong GPA. Great time management skills and must be well organized.

Strong interest in science, learning and working in a fast paced environment.

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

For consideration, please submit your resume and cover letter referencing job 170AB to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

144AC Project Manager (Part-Time Consultant/Contract Role)

 

Overview

We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever. Our Project Manager will work with our research, manufacturing and clinical teams to manage key research and development programs. In this part-time role, the successful candidate will develop and maintain overall project plans for research activities including budgets, strategy implementation, timelines, resource analysis and project plans. Key work will cover a wide range of activities including developing strategies to support basic research to IND filing, new indication analysis, external collaboration management, and clinical and CMC support for BLA submissions. This role could be a consultant or a contractor and will be dedicated approximately 20 – 25 hours per week.
 
This role will:

  • Perform the role of project manager for all R & D projects
  • Standardize project management practices
  • Coach and mentor project leaders on best practices in project management as it relates to key aspects of the drug discovery and development process.
  • Assist members of the team to manage an array of external collaborations in support of the goals and objectives of the relevant project teams.
  • Manage and track program progress.
  • Coordinate and encourage communication across company and engage stakeholders with a ‘solution-oriented’ focus.
  • Identify and implement tools, processes, standards, best-practices, dash boards.
  • Maintain project documentation files to include data files, presentations, meeting minutes, action items, schedules, contracts, budgets.
  • Provide support during the preparation, implementation and follow up for board meetings, regulatory meetings and team meetings including preparing presentations and minutes and archiving related follow-up.

 

Requirements

  • Strong understanding of project management methodologies and tools including MS Project.
  • Understanding of disciplined drug discovery, product development and program management processes.
  • Demonstrated time management, decision-making, presentation and organization skills required. Ability to manage multiple projects, prioritize and analyze work flows for efficiency.
  • BS/MS Degree with at least 5+ years of industry experience in project management in the pharmaceutical/biotech arena.
  • Strong technical background and knowledge of biologics development, preferably focused around monoclonal antibodies and Fc fusion proteins, or related therapeutic modalities.



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#144AC” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
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143MP Associate Scientist, Analytical and Formulations Development

 

Position Summary

We are currently seeking an Associate Scientist to join our Process Sciences team. The successful candidate will perform analytical and formulation development activities to advance our clinical programs and support process development and characterization for pre-clinical candidates.
 

Qualifications

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired. Experience with MS software is required (Word, Excel, PowerPoint), and scientific software (ChemStation, Astra, Dynamics, Empower, MassHunter, 32 Karat) is preferred.
 

  • Experienced in developing analytical methods with minimal supervision for testing and characterization of mAbs and recombinant proteins using techniques such as UV-vis spectrometry, SDS-PAGE, Western blot, HPLC (SEC-MALS, CEX, RP), and CE
  • Experienced in formulation development process and knowledge of biophysical and light obscuration methods
  • Working knowledge and understanding of GxP and CMC regulatory requirements related to biologics manufacturing and control
  • Experience with analytical method transfers and interfacing with CRO/CMOs for testing, release and stability studies
  • Experienced in authoring detailed analytical reports, and providing high quality data for regulatory submissions
  • Extremely detail-oriented and diligent in experimental design, data analysis and review
  • Organized and able to execute multiple activities in parallel
  • High level of motivation and initiative
  • Excellent written and verbal communication skills
  • Works well in a dynamic, high energy, fast-paced team and collaborate with cross-functional groups
  • B.S. with 5+ years or M.S. with 1+ years of biopharmaceutical industry experience or equivalent



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#143MP” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
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142SC Research Associate, Flow Cytometry

 

Position Summary

We are seeking to add an enthusiastic and highly motivated research associate to our team focused on the design and development of novel medicines based on our research into new biological pathways. In this position, you will play an important role in the drug discovery process through your ability to work with in vitro cell based assays, and especially flow cytometry. You will design, execute and analyze complex experiments, including multi-color flow cytometry from both in vivo and in vitro studies. Key areas of focus for this position will be in analysis of pathways in immunology including immunophenotyping and characterization of activated immune subsets from human and mouse samples. You will learn to design, execute, summarize and present the results of your experiments to the research team.
 

Experience

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast- paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Extensive experience working with cells in culture as well as flow cytometry experience using human primary cells or ex vivo mouse samples is required. The candidate should also have experience purifying cellular populations from human and mouse blood and/or tissue using magnetic separation techniques. A solid understanding of flow compensation and data analysis is preferred.
 
The ideal candidate will have:

  • Extensive experience with culture of mammalian cells, and the ability to perform cell-based assays
  • Extensive experience in designing & conducting multi-color flow cytometry experiments
  • Experience with immunophenotyping adaptive and innate immune cell populations in human and/or mouse
  • Background in maintenance and upkeep of a flow cytometer
  • Experience analyzing flow cytometry data using FlowJo platform preferred
  • Experience quantitating protein analytes using ELISA and/or multiplex immunoassay platforms preferred
  • Strong analytical skills and problem solving ability
  • Strong verbal and written communication skills
  • Should be able to work with minimal supervision and a high level of initiative
  • Must be attentive to details
  • Must be skilled in FlowJo, Windows, Microsoft Office and GraphPad Prism
  • B.Sc. or M.Sc. in Immunology/Biology or a related discipline with minimum of 2+ years of experience.



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#142SC” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

141SC Research Associate, Pharmacology & Immunology

 

Position Summary

We are seeking to add an enthusiastic and highly motivated research associate to our team focused on the design and development of novel medicines based on our research into new biological pathways. In this position, you will play an important role in the drug discovery process through your ability to work with a variety of cell based assays. You will learn to apply cell-based and in vivo assays, using signaling-based read-outs, microscopy, and flow cytometry to support our novel research and pre-clinical development of therapeutic candidates. Cell- based assay development and optimization will be an area of special focus in this position, including cell signaling-based experiments in cultured primary cells to support mechanism-of- action and biomarker studies. You will learn to design, execute, summarize and present the results of your experiments to the research team.
 

Experience

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast- paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Extensive experience working with cells in culture as well as flow cytometry experience using is required, as well as a solid understanding of the assay development process. Sufficiently deep understanding and hands-on experience with data analysis and corresponding software to support assays of this type (Excel, GraphPad Prism) is required.
 
The ideal candidate will have:

  • Extensive experience using aseptic technique to culture human primary and/or cell lines
  • Experience quantitating protein analytes using ELISA, multiplex immunoassay platforms, and/or Western Blot
  • Experience with RNA isolation and quantifying gene expression by qPCR
  • Flow cytometry experience preferred
  • Experience in immunocytochemistry techniques preferred
  • Strong analytical skills and problem solving ability
  • Strong verbal and written communication skills
  • Should work with minimal supervision and a high level of initiative
  • Must be attentive to details
  • Must be skilled in Windows and Microsoft Office (including Word, PowerPoint and Excel) and GraphPad Prism
  • B.Sc. or M.Sc. in Immunology/Biology or a related discipline with minimum of 2+ years of experience.



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#141SC” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

140DL Scientist, Protein Production & Process Development

 

Position Summary

We are currently seeking a Scientist to join the Biologics Development and Manufacturing team. The successful candidate will perform protein production and process development activities to generate high quality proteins for research use, and support manufacturing process development for clinical candidates. Laboratory responsibilities include both upstream production, primarily with mammalian cell culture processes, and downstream protein purification.
 

Qualifications

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired. Experience with MS software is required (Word, Excel, PowerPoint), and scientific software (DeltaV, Unicorn) is preferred.
 
The ideal candidate will have:

  • Ph.D. with 0-3 years of biopharmaceutical industry experience or equivalent
  • Experience in mammalian cell culture process development, aseptic processing and bioreactor operation. Experience with microbial fermentation processes is a plus.
  • Experience in development and execution of protein purification processes utilizing chromatography and filtration based technologies
  • Molecular biology skills (DNA cloning and expression) are a plus
  • Experience in harvest, clarification, and recovery processes
  • Knowledge of cGMP and regulatory requirements related to biologics manufacturing and controls
  • Extremely detail-oriented and diligent in experimental design, data analysis and review
  • Organized and able to execute multiple activities in parallel
  • High level of motivation and initiative
  • Excellent written and verbal communication skills
  • Work well in a dynamic, high energy, fast-paced team and collaborate with cross-functional groups



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#140DL” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

139JB Associate Director / Director, Investor Relations and Corporate Communications

 

Position Summary

Reporting to the Chief Financial Officer, the successful candidate will be responsible for executing the global investor relations program (in collaboration with the Chief Executive). This will include executing strategic planning, corporate analysis and portfolio planning initiatives. This role will be responsible for developing and executing the IR strategy, operating plans, budget, and global IR program. The primary operating objective of the IR program is to educate and update investors and security analysts about the company to achieve a fair relative stock price. The primary objective of the Strategic Planning program is to engage in scenario analysis, market assessment, forecasting and portfolio planning for the Company.
 

Primary Responsibilities

Investor Relations Strategy, Plan, and Execution

  • Develops the IR strategy, operating plan, and budget in collaboration with the CFO
  • Executes the IR program
  • Educates and updates investors and analysts
  • Executes the creation of publications and electronic media used in the IR program. Supervises the data collection, analysis, writing and editing, and production of those materials.
  • Leads presentations and discussions in the IR program
  • Educates and updates investors and analysts
  • Keeps shareholders knowledgeable about the company
  • Finds, supports, and encourages prospective investors by broadening awareness and interest through conferences, presentations, meetings, media, and mailings
  • Responds to investor targets-of-opportunity created by presentations, meetings, and media
  • Hosts conference calls, prepares conference call scripts and practice questions (with answers when needed), and leads practice sessions
  • Uses statistical targeting to identify good-fit institutional investors; contacts the analysts at those institutions to verify possible interest and to encourage interest and investment
  • In collaboration with the CFO, supports the investors’ decision-making processes through visits to institutions, individual meetings, visits by analysts and investors to company plants, and visits with appropriate other senior leaders
  • Supports security analysts in brokerage firms
  • Contracts for and directs the capital markets database and intelligence system that supports the investor relations program
  • Creates or assists in creating the publications and electronic media used in the IR program
  • Annual report: design, production, and delivery
  • Quarterly results and other news releases: collaborates in creating
  • Periodic update of the outlook for the quarter and or year results: collaborates with CFO
  • SEC filings: collaborates with the CEO, CFO, and VP Legal
  • Substitute leader of conference calls, both for quarterly results and special events
  • Executes webcasts, usually in conjunction with conference calls and investment conference presentations. Contracts for webcasts
  • Collaborates with the CFO on the IR website section and content
  • Supports the IR website archive of historical information for investors
  • Collaborates with company marketing and company advertising
  • Assists with media news stories
  • Supports the Annual Meeting of Analysts & Investors
  • Supports presentations at broker-sponsored conferences and meetings
  • Supports presentations at company-hosted conferences and meetings
  • Discussions with analysts and review of draft reports for accuracy of publicly disclosed information
  • Supports visits by the CFO and other senior leaders to institutional investors
  • Supports visits by investors to the company headquarters
  • Gives presentations at internal company meetings

Strategic Planning

  • Collaborates on company decisions that will create value for shareholders
  • Provides competitive intelligence from Wall Street to the other company leaders and appropriate operations. Collaborates with Business Development.
  • Performs market studies and analyses
  • Collaborates with Financial Reporting, Financial Analysis, Public Relations, Advertising, Marketing, Legal, and others, as needed
  • Collaborates on and assists with trade shows and special events
  • Assists with annual, general, and special shareholder meetings (collaborates with the General Counsel, Secretary, and head of Shareholder Services for those meetings, as needed)

Experience and Education Requirements

  • 7+ years’ of experience in investor relations, finance, marketing, strategy consulting, planning and development, or corporate communication positions for a public company or professional services firm
  • Direct experience with the bio-pharmaceutical industry
  • Outstanding financial and investment analysis skills, oral and written communication skills, and presentation ability
  • A clear and thorough understanding of the financial modeling techniques used by security analysts to project a company’s operating and financial performance and the resulting value for its stock
  • An in-depth understanding of the financial and investment markets and the ability to establish new relationships in new industries quickly
  • A strong understanding of the bio-pharmaceutical industry
  • A good understanding of strategic communication, public relations, marketing, advertising, and the media
  • An emerging reputation with the investment community, based on credibility, consistency, visibility, access, and depth and breadth of knowledge
  • Strong interpersonal skills, superior intellect, and an outstanding ability to communicate using these qualities and skills
  • An energetic, efficient, and resourceful team player and individual contributor
  • An active and effective leader
  • A person with an insatiable appetite to learn more
  • College degree required, with a master’s degree highly desirable; scientific background preferred



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#139JB” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

137YB Sr. Research Associate, Protein Production & Process Development

 

Position Summary

We are currently seeking a Senior Research Associate to join the Biologics Development and Manufacturing team. The successful candidate will perform protein production and process development activities to generate high quality proteins for research use, and support manufacturing process development for clinical candidates. Laboratory responsibilities include both upstream production, primarily with mammalian cell culture processes, and downstream protein purification.
 

Experience and Education Requirements

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired. Experience with scientific software (Excel, GraphPad Prism) is required.
 
The ideal candidate will have:

  • BS with 5+ years of biopharmaceutical industry experience or equivalent
  • Experience in development and execution of mammalian cell culture processes. Experience with microbial fermentation processes is a plus.
  • Experience in development and execution of protein purification processes utilizing chromatography and filtration based technologies
  • Experience in harvest, clarification, and recovery processes
  • Knowledge of cGMP and regulatory requirements related to biologics manufacturing
    and controls
  • Extremely detail-oriented and diligent in experimental design, data analysis and review
  • Organized and able to execute multiple activities in parallel
  • High level of motivation and initiative
  • Excellent written and verbal communication skills
  • Work well in a dynamic, high energy, fast-paced team and collaborate with cross-functional groups



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#137YB” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

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TOGETHER WE believe that MicroRNA therapeutics will become a major new class of drugs. We are focused on harnessing their power to target multiple pathways of disease.

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Together, the Regulus team is leading the way in the discovery and development of microRNA therapeutics.

Regulus was formed in September 2007 by Alnylam Pharmaceuticals (NASDAQ:ALNY) and Isis Pharmaceuticals, now Ionis Pharmaceuticals (NASDAQ:IONS) and has continued to build upon our thought leadership, knowledge base, intellectual property and a clear focus to become the leader in microRNA therapeutics. The Regulus systems approach has mapped more than 6,000 diseases to specific tissue pathologies as well as their driver genes. It has linked specific microRNAs to the regulation of those driver genes and tissue disease states. Regulus has benefited from the collective therapeutic RNA expertise of its founding companies, including established proprietary oligonucleotide-based technologies, and broad and dominant intellectual property estates specific to chemically modified oligonucleotides. Regulus can access over 850 patents and patent applications in oligonucleotide technologies as well as owning over 200 patents and patent applications directed to microRNA delivery, manufacturing and specific technologies.

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Sweden 449,964 410,928
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