144AC Project Manager (Part-Time Consultant/Contract Role)

 

Overview

We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever. Our Project Manager will work with our research, manufacturing and clinical teams to manage key research and development programs. In this part-time role, the successful candidate will develop and maintain overall project plans for research activities including budgets, strategy implementation, timelines, resource analysis and project plans. Key work will cover a wide range of activities including developing strategies to support basic research to IND filing, new indication analysis, external collaboration management, and clinical and CMC support for BLA submissions. This role could be a consultant or a contractor and will be dedicated approximately 20 – 25 hours per week.
 
This role will:

  • Perform the role of project manager for all R & D projects
  • Standardize project management practices
  • Coach and mentor project leaders on best practices in project management as it relates to key aspects of the drug discovery and development process.
  • Assist members of the team to manage an array of external collaborations in support of the goals and objectives of the relevant project teams.
  • Manage and track program progress.
  • Coordinate and encourage communication across company and engage stakeholders with a ‘solution-oriented’ focus.
  • Identify and implement tools, processes, standards, best-practices, dash boards.
  • Maintain project documentation files to include data files, presentations, meeting minutes, action items, schedules, contracts, budgets.
  • Provide support during the preparation, implementation and follow up for board meetings, regulatory meetings and team meetings including preparing presentations and minutes and archiving related follow-up.

 

Requirements

  • Strong understanding of project management methodologies and tools including MS Project.
  • Understanding of disciplined drug discovery, product development and program management processes.
  • Demonstrated time management, decision-making, presentation and organization skills required. Ability to manage multiple projects, prioritize and analyze work flows for efficiency.
  • BS/MS Degree with at least 5+ years of industry experience in project management in the pharmaceutical/biotech arena.
  • Strong technical background and knowledge of biologics development, preferably focused around monoclonal antibodies and Fc fusion proteins, or related therapeutic modalities.



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#144AC” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

143MP Associate Scientist, Analytical and Formulations Development

 

Position Summary

We are currently seeking an Associate Scientist to join our Process Sciences team. The successful candidate will perform analytical and formulation development activities to advance our clinical programs and support process development and characterization for pre-clinical candidates.
 

Qualifications

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired. Experience with MS software is required (Word, Excel, PowerPoint), and scientific software (ChemStation, Astra, Dynamics, Empower, MassHunter, 32 Karat) is preferred.
 

  • Experienced in developing analytical methods with minimal supervision for testing and characterization of mAbs and recombinant proteins using techniques such as UV-vis spectrometry, SDS-PAGE, Western blot, HPLC (SEC-MALS, CEX, RP), and CE
  • Experienced in formulation development process and knowledge of biophysical and light obscuration methods
  • Working knowledge and understanding of GxP and CMC regulatory requirements related to biologics manufacturing and control
  • Experience with analytical method transfers and interfacing with CRO/CMOs for testing, release and stability studies
  • Experienced in authoring detailed analytical reports, and providing high quality data for regulatory submissions
  • Extremely detail-oriented and diligent in experimental design, data analysis and review
  • Organized and able to execute multiple activities in parallel
  • High level of motivation and initiative
  • Excellent written and verbal communication skills
  • Works well in a dynamic, high energy, fast-paced team and collaborate with cross-functional groups
  • B.S. with 5+ years or M.S. with 1+ years of biopharmaceutical industry experience or equivalent



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#143MP” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

142SC Research Associate, Flow Cytometry

 

Position Summary

We are seeking to add an enthusiastic and highly motivated research associate to our team focused on the design and development of novel medicines based on our research into new biological pathways. In this position, you will play an important role in the drug discovery process through your ability to work with in vitro cell based assays, and especially flow cytometry. You will design, execute and analyze complex experiments, including multi-color flow cytometry from both in vivo and in vitro studies. Key areas of focus for this position will be in analysis of pathways in immunology including immunophenotyping and characterization of activated immune subsets from human and mouse samples. You will learn to design, execute, summarize and present the results of your experiments to the research team.
 

Experience

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast- paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Extensive experience working with cells in culture as well as flow cytometry experience using human primary cells or ex vivo mouse samples is required. The candidate should also have experience purifying cellular populations from human and mouse blood and/or tissue using magnetic separation techniques. A solid understanding of flow compensation and data analysis is preferred.
 
The ideal candidate will have:

  • Extensive experience with culture of mammalian cells, and the ability to perform cell-based assays
  • Extensive experience in designing & conducting multi-color flow cytometry experiments
  • Experience with immunophenotyping adaptive and innate immune cell populations in human and/or mouse
  • Background in maintenance and upkeep of a flow cytometer
  • Experience analyzing flow cytometry data using FlowJo platform preferred
  • Experience quantitating protein analytes using ELISA and/or multiplex immunoassay platforms preferred
  • Strong analytical skills and problem solving ability
  • Strong verbal and written communication skills
  • Should be able to work with minimal supervision and a high level of initiative
  • Must be attentive to details
  • Must be skilled in FlowJo, Windows, Microsoft Office and GraphPad Prism
  • B.Sc. or M.Sc. in Immunology/Biology or a related discipline with minimum of 2+ years of experience.



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#142SC” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

141SC Research Associate, Pharmacology & Immunology

 

Position Summary

We are seeking to add an enthusiastic and highly motivated research associate to our team focused on the design and development of novel medicines based on our research into new biological pathways. In this position, you will play an important role in the drug discovery process through your ability to work with a variety of cell based assays. You will learn to apply cell-based and in vivo assays, using signaling-based read-outs, microscopy, and flow cytometry to support our novel research and pre-clinical development of therapeutic candidates. Cell- based assay development and optimization will be an area of special focus in this position, including cell signaling-based experiments in cultured primary cells to support mechanism-of- action and biomarker studies. You will learn to design, execute, summarize and present the results of your experiments to the research team.
 

Experience

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast- paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Extensive experience working with cells in culture as well as flow cytometry experience using is required, as well as a solid understanding of the assay development process. Sufficiently deep understanding and hands-on experience with data analysis and corresponding software to support assays of this type (Excel, GraphPad Prism) is required.
 
The ideal candidate will have:

  • Extensive experience using aseptic technique to culture human primary and/or cell lines
  • Experience quantitating protein analytes using ELISA, multiplex immunoassay platforms, and/or Western Blot
  • Experience with RNA isolation and quantifying gene expression by qPCR
  • Flow cytometry experience preferred
  • Experience in immunocytochemistry techniques preferred
  • Strong analytical skills and problem solving ability
  • Strong verbal and written communication skills
  • Should work with minimal supervision and a high level of initiative
  • Must be attentive to details
  • Must be skilled in Windows and Microsoft Office (including Word, PowerPoint and Excel) and GraphPad Prism
  • B.Sc. or M.Sc. in Immunology/Biology or a related discipline with minimum of 2+ years of experience.



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#141SC” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

140DL Scientist, Protein Production & Process Development

 

Position Summary

We are currently seeking a Scientist to join the Biologics Development and Manufacturing team. The successful candidate will perform protein production and process development activities to generate high quality proteins for research use, and support manufacturing process development for clinical candidates. Laboratory responsibilities include both upstream production, primarily with mammalian cell culture processes, and downstream protein purification.
 

Qualifications

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired. Experience with MS software is required (Word, Excel, PowerPoint), and scientific software (DeltaV, Unicorn) is preferred.
 
The ideal candidate will have:

  • Ph.D. with 0-3 years of biopharmaceutical industry experience or equivalent
  • Experience in mammalian cell culture process development, aseptic processing and bioreactor operation. Experience with microbial fermentation processes is a plus.
  • Experience in development and execution of protein purification processes utilizing chromatography and filtration based technologies
  • Molecular biology skills (DNA cloning and expression) are a plus
  • Experience in harvest, clarification, and recovery processes
  • Knowledge of cGMP and regulatory requirements related to biologics manufacturing and controls
  • Extremely detail-oriented and diligent in experimental design, data analysis and review
  • Organized and able to execute multiple activities in parallel
  • High level of motivation and initiative
  • Excellent written and verbal communication skills
  • Work well in a dynamic, high energy, fast-paced team and collaborate with cross-functional groups



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#140DL” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

139JB Associate Director / Director, Investor Relations and Corporate Communications

 

Position Summary

Reporting to the Chief Financial Officer, the successful candidate will be responsible for executing the global investor relations program (in collaboration with the Chief Executive). This will include executing strategic planning, corporate analysis and portfolio planning initiatives. This role will be responsible for developing and executing the IR strategy, operating plans, budget, and global IR program. The primary operating objective of the IR program is to educate and update investors and security analysts about the company to achieve a fair relative stock price. The primary objective of the Strategic Planning program is to engage in scenario analysis, market assessment, forecasting and portfolio planning for the Company.
 

Primary Responsibilities

Investor Relations Strategy, Plan, and Execution

  • Develops the IR strategy, operating plan, and budget in collaboration with the CFO
  • Executes the IR program
  • Educates and updates investors and analysts
  • Executes the creation of publications and electronic media used in the IR program. Supervises the data collection, analysis, writing and editing, and production of those materials.
  • Leads presentations and discussions in the IR program
  • Educates and updates investors and analysts
  • Keeps shareholders knowledgeable about the company
  • Finds, supports, and encourages prospective investors by broadening awareness and interest through conferences, presentations, meetings, media, and mailings
  • Responds to investor targets-of-opportunity created by presentations, meetings, and media
  • Hosts conference calls, prepares conference call scripts and practice questions (with answers when needed), and leads practice sessions
  • Uses statistical targeting to identify good-fit institutional investors; contacts the analysts at those institutions to verify possible interest and to encourage interest and investment
  • In collaboration with the CFO, supports the investors’ decision-making processes through visits to institutions, individual meetings, visits by analysts and investors to company plants, and visits with appropriate other senior leaders
  • Supports security analysts in brokerage firms
  • Contracts for and directs the capital markets database and intelligence system that supports the investor relations program
  • Creates or assists in creating the publications and electronic media used in the IR program
  • Annual report: design, production, and delivery
  • Quarterly results and other news releases: collaborates in creating
  • Periodic update of the outlook for the quarter and or year results: collaborates with CFO
  • SEC filings: collaborates with the CEO, CFO, and VP Legal
  • Substitute leader of conference calls, both for quarterly results and special events
  • Executes webcasts, usually in conjunction with conference calls and investment conference presentations. Contracts for webcasts
  • Collaborates with the CFO on the IR website section and content
  • Supports the IR website archive of historical information for investors
  • Collaborates with company marketing and company advertising
  • Assists with media news stories
  • Supports the Annual Meeting of Analysts & Investors
  • Supports presentations at broker-sponsored conferences and meetings
  • Supports presentations at company-hosted conferences and meetings
  • Discussions with analysts and review of draft reports for accuracy of publicly disclosed information
  • Supports visits by the CFO and other senior leaders to institutional investors
  • Supports visits by investors to the company headquarters
  • Gives presentations at internal company meetings

Strategic Planning

  • Collaborates on company decisions that will create value for shareholders
  • Provides competitive intelligence from Wall Street to the other company leaders and appropriate operations. Collaborates with Business Development.
  • Performs market studies and analyses
  • Collaborates with Financial Reporting, Financial Analysis, Public Relations, Advertising, Marketing, Legal, and others, as needed
  • Collaborates on and assists with trade shows and special events
  • Assists with annual, general, and special shareholder meetings (collaborates with the General Counsel, Secretary, and head of Shareholder Services for those meetings, as needed)

Experience and Education Requirements

  • 7+ years’ of experience in investor relations, finance, marketing, strategy consulting, planning and development, or corporate communication positions for a public company or professional services firm
  • Direct experience with the bio-pharmaceutical industry
  • Outstanding financial and investment analysis skills, oral and written communication skills, and presentation ability
  • A clear and thorough understanding of the financial modeling techniques used by security analysts to project a company’s operating and financial performance and the resulting value for its stock
  • An in-depth understanding of the financial and investment markets and the ability to establish new relationships in new industries quickly
  • A strong understanding of the bio-pharmaceutical industry
  • A good understanding of strategic communication, public relations, marketing, advertising, and the media
  • An emerging reputation with the investment community, based on credibility, consistency, visibility, access, and depth and breadth of knowledge
  • Strong interpersonal skills, superior intellect, and an outstanding ability to communicate using these qualities and skills
  • An energetic, efficient, and resourceful team player and individual contributor
  • An active and effective leader
  • A person with an insatiable appetite to learn more
  • College degree required, with a master’s degree highly desirable; scientific background preferred



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#139JB” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

137YB Sr. Research Associate, Protein Production & Process Development

 

Position Summary

We are currently seeking a Senior Research Associate to join the Biologics Development and Manufacturing team. The successful candidate will perform protein production and process development activities to generate high quality proteins for research use, and support manufacturing process development for clinical candidates. Laboratory responsibilities include both upstream production, primarily with mammalian cell culture processes, and downstream protein purification.
 

Experience and Education Requirements

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired. Experience with scientific software (Excel, GraphPad Prism) is required.
 
The ideal candidate will have:

  • BS with 5+ years of biopharmaceutical industry experience or equivalent
  • Experience in development and execution of mammalian cell culture processes. Experience with microbial fermentation processes is a plus.
  • Experience in development and execution of protein purification processes utilizing chromatography and filtration based technologies
  • Experience in harvest, clarification, and recovery processes
  • Knowledge of cGMP and regulatory requirements related to biologics manufacturing
    and controls
  • Extremely detail-oriented and diligent in experimental design, data analysis and review
  • Organized and able to execute multiple activities in parallel
  • High level of motivation and initiative
  • Excellent written and verbal communication skills
  • Work well in a dynamic, high energy, fast-paced team and collaborate with cross-functional groups



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#137YB” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
PDF VERSION

styles

Testing display of HTML elements – h1 tag

This is a test paragraph.

This is 2nd level heading – h2 tag

This is a test paragraph.

This is 3rd level heading – h3 tag

This is a test paragraph.

This is 3rd level heading – h3 tag with class .even

This is 3rd level heading – h3 tag with class .odd

This is 4th level heading – h4 tag

This is a test paragraph.

This is 5th level heading

This is a test paragraph.

This is 6th level heading

This is a test paragraph.

Basic block level elements

This is the caption for the image
This is the caption for the image

TOGETHER WE believe that MicroRNA therapeutics will become a major new class of drugs. We are focused on harnessing their power to target multiple pathways of disease.

This is a normal paragraph. To add some length to it, let us mention that this page was primarily written for testing the effect of user style sheets. You can use it for various other purposes as well, like just checking how your browser displays various HTML elements by default. It can also be useful when testing conversions from HTML format to other formats, since some elements can go wrong then. Dysregulated microRNA expression is a key factor in many complex multi-factoral diseases, including inflammatory disease, fibrosis, metabolic disease and cancer. microRNA therapeutics are oligonucleotides that modulate the function of microRNAs, correcting the imbalance of gene expression and associated cellular pathways to treat a broad range human disease.This is another paragraph. I think it needs to be added that the set of elements tested is not exhaustive in any sense.

Balboa Park 1915 caption
Balboa Park 1915 caption

microRNAs are members of a large class of non-coding RNAs of approximately 22 nucleotides in length that regulate most genes in the genome. A single microRNA can target and regulate up to hundreds of genes and these genes are involved in biological networks or pathways.I have selected those elements for which it can make sense to write user style sheet rules, in my opinion.

Together, the Regulus team is leading the way in the discovery and development of microRNA therapeutics.

Regulus was formed in September 2007 by Alnylam Pharmaceuticals (NASDAQ:ALNY) and Isis Pharmaceuticals, now Ionis Pharmaceuticals (NASDAQ:IONS) and has continued to build upon our thought leadership, knowledge base, intellectual property and a clear focus to become the leader in microRNA therapeutics. The Regulus systems approach has mapped more than 6,000 diseases to specific tissue pathologies as well as their driver genes. It has linked specific microRNAs to the regulation of those driver genes and tissue disease states. Regulus has benefited from the collective therapeutic RNA expertise of its founding companies, including established proprietary oligonucleotide-based technologies, and broad and dominant intellectual property estates specific to chemically modified oligonucleotides. Regulus can access over 850 patents and patent applications in oligonucleotide technologies as well as owning over 200 patents and patent applications directed to microRNA delivery, manufacturing and specific technologies.

This is a block quotation containing a single paragraph. Well, not quite, since this is not really quoted text, but I hope you understand the point. After all, this page does not use HTML markup very normally anyway.

Regulus Therapeutics is located in La Jolla, California and is led by a seasoned executive team and board of directors, with proven expertise in corporate management, business operations, drug discovery, development and commercialization.

Lists

  • One.
  • Two.
  • Three. Well, probably this list item should be longer. Note that for short items lists look better if they are compactly presented, whereas for long items, it would be better to have more vertical spacing between items.
  • Four. This is the last item in this list. Let us terminate the list now without making any more fuss about it.

lorum ipsum text here to show odd

lorem upsum to show even


This is a paragraph before a numbered list (ol). Note that the spacing between a paragraph and a list before or after that is hard to tune in a user style sheet. You can””t guess which paragraphs are logically related to a list, e.g. as a “list header”.

  1. One.
  2. Two.
  3. Three. Well, probably this list item should be longer. Note that if items are short, lists look better if they are compactly presented, whereas for long items, it would be better to have more vertical spacing between items.
  4. Four. This is the last item in this list. Let us terminate the list now without making any more fuss about it.

Links

This is a text paragraph that contains some inline links. Generally, inline links (as opposite to e.g. links lists) are problematic from the usability perspective, but they may have use as “incidental”, less relevant links. See the document Links Want To Be Links.

Buttons

Tables

The following table has a caption. The first column contain table header cells (th elements) only; other cells are data cells with even/odd classes.

Sample table: Areas of the Nordic countries, in sq km
Country Total area Land area
Denmark 43,070 42,370
Finland 337,030 305,470
Iceland 103,000 100,250
Norway 324,220 307,860
Sweden 449,964 410,928

David J. King, Ph.D.

David J. King, Ph.D. has served as our Chief Scientific Officer since February 2018. Prior to that, he served as our Senior Vice President, Research from September 2016 to February 2018. David’s industry experience is highlighted by his tenures at Medarex, Inc., (acquired by Bristol-Myers Squibb in 2009) and Celltech Therapeutics Ltd. (acquired by UCB in 2004). At Medarex, he led programs to identify therapeutic antibodies and played a key role in programs targeting novel biologics (including PD-1), and at Celltech, he directed the protein biochemistry and antibody engineering activities that led to the discovery and development of Cimzia® (TNF antagonist). After Medarex, Dr. King served as Chief Scientific Officer at AnaptysBio, Inc. from November 2008 to February 2016 where he led research that developed a novel technology for generating antibody therapeutics, which was successfully used to generate innovative clinical candidates for a number of pharmaceutical partnerships and for internal development. Most recently, Dr. King served as Senior Vice President of Research at Tunitas Therapeutics, where he led the company’s research and preclinical activities from February 2016 to September 2016. Dr. King received his B.S. from the University of Warwick and his Ph.D. from the University of Surrey, both in the United Kingdom, and was a Glaxo Group Research postdoctoral fellow.

© 2007 - 2020   aTyr Pharma.   Legal   Privacy Policy