Career Opportunities

Open Positions:

143MP Associate Scientist, Analytical and Formulations Development

 

Position Summary

We are currently seeking an Associate Scientist to join our Process Sciences team. The successful candidate will perform analytical and formulation development activities to advance our clinical programs and support process development and characterization for pre-clinical candidates.
 

Qualifications

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired. Experience with MS software is required (Word, Excel, PowerPoint), and scientific software (ChemStation, Astra, Dynamics, Empower, MassHunter, 32 Karat) is preferred.
 

  • Experienced in developing analytical methods with minimal supervision for testing and characterization of mAbs and recombinant proteins using techniques such as UV-vis spectrometry, SDS-PAGE, Western blot, HPLC (SEC-MALS, CEX, RP), and CE
  • Experienced in formulation development process and knowledge of biophysical and light obscuration methods
  • Working knowledge and understanding of GxP and CMC regulatory requirements related to biologics manufacturing and control
  • Experience with analytical method transfers and interfacing with CRO/CMOs for testing, release and stability studies
  • Experienced in authoring detailed analytical reports, and providing high quality data for regulatory submissions
  • Extremely detail-oriented and diligent in experimental design, data analysis and review
  • Organized and able to execute multiple activities in parallel
  • High level of motivation and initiative
  • Excellent written and verbal communication skills
  • Works well in a dynamic, high energy, fast-paced team and collaborate with cross-functional groups
  • B.S. with 5+ years or M.S. with 1+ years of biopharmaceutical industry experience or equivalent



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#143MP” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
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142SC Research Associate, Flow Cytometry

 

Position Summary

We are seeking to add an enthusiastic and highly motivated research associate to our team focused on the design and development of novel medicines based on our research into new biological pathways. In this position, you will play an important role in the drug discovery process through your ability to work with in vitro cell based assays, and especially flow cytometry. You will design, execute and analyze complex experiments, including multi-color flow cytometry from both in vivo and in vitro studies. Key areas of focus for this position will be in analysis of pathways in immunology including immunophenotyping and characterization of activated immune subsets from human and mouse samples. You will learn to design, execute, summarize and present the results of your experiments to the research team.
 

Experience

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast- paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Extensive experience working with cells in culture as well as flow cytometry experience using human primary cells or ex vivo mouse samples is required. The candidate should also have experience purifying cellular populations from human and mouse blood and/or tissue using magnetic separation techniques. A solid understanding of flow compensation and data analysis is preferred.
 
The ideal candidate will have:

  • Extensive experience with culture of mammalian cells, and the ability to perform cell-based assays
  • Extensive experience in designing & conducting multi-color flow cytometry experiments
  • Experience with immunophenotyping adaptive and innate immune cell populations in human and/or mouse
  • Background in maintenance and upkeep of a flow cytometer
  • Experience analyzing flow cytometry data using FlowJo platform preferred
  • Experience quantitating protein analytes using ELISA and/or multiplex immunoassay platforms preferred
  • Strong analytical skills and problem solving ability
  • Strong verbal and written communication skills
  • Should be able to work with minimal supervision and a high level of initiative
  • Must be attentive to details
  • Must be skilled in FlowJo, Windows, Microsoft Office and GraphPad Prism
  • B.Sc. or M.Sc. in Immunology/Biology or a related discipline with minimum of 2+ years of experience.



Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing “#142SC” to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
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