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Career Opportunities


Open Positions:

105KO Senior Scientist, Pharmacokinetics and Translational Biology

Position Summary

The successful candidate will have a strong desire to move novel therapies forward into clinical studies and will play a key role in translating our research data to the clinical setting. We seek an expert in pharmacokinetics (PK), pharmacodynamics (PD) and modeling of diverse pre-clinical datasets for prediction of clinical parameters. In this role, you will use your experience to independently develop and refine PK/PD models based on data from multiple species and in vitro assays. A key focus of the role will be to propose, interrogate experimentally and qualify potential PD and disease-associated biomarkers to support our clinical programs. The successful candidate will also engage and communicate effectively within an interdisciplinary scientific and management team.

Required background

The role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. Extensive experience developing PK/PD models for protein therapeutics and a history of success as evidenced by a publication record in top tier journals is required.
The ideal candidate will have:

  • Ph.D. in biology, pharmacokinetics, pharmacology, or related discipline
  • Minimum of 5 years of relevant industry experience, including research and development of biologic therapeutics.
  • Experience with pharmacokinetic modeling of biologics and additionally experience with appropriate software tools (e.g., Phoenix WinNonlin, MATLAB/Symbiology etc.) is strongly preferred.
  • Proven track record in translational research that demonstrates development of pre-clinical/clinical biomarkers and/or delivery of companion diagnostics to the clinic
  • Strong critical thinking and problem solving skills, and a track record of publications in high quality journals
  • Strong organizational and project skills and the ability to work with minimal supervision and a high level of initiative.
  • Excellent verbal and written communication skills.





Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job (105KO) to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
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113DK Head of Immunology

Position Summary

We are seeking a motivated, industry-experienced scientist to lead a talented group of immunologists. This individual will have an established reputation for world-class science, considerable expertise in cellular immunology, and the drive and enthusiasm to lead programs toward clinical evaluation. They will play a key role in enhancing our understanding of novel biological pathways and developing a pipeline of biologic therapeutics. This individual will help conceptualize and lead the design and execution of pivotal experimental studies, and assist in cross-functional development of our strategy.

  • Lead a world-class immunology team to elucidate novel immunological mechanisms as related to Physiocrine biology
  • Lead drug discovery teams toward novel clinical candidates
  • Lead in-depth characterization of novel Physiocrine biology as it relates to modulation of immune responses in vitro and in vivo. Design and oversee well-controlled experiments to advance our understanding of pathways and product candidates
  • Assist with translational studies and coordinate development and testing of relevant assays to determine biological outcomes (including biomarker identification, pharmacodynamic readouts and mechanistic studies)
  • Manage collaborative relationships with project leads, internal and external groups and leadership to resource and advance projects.
  • Publish on relevant and important data

Experience and Education Requirements

  • Proven scientific and technical leader with a track-record of significant contributions to drug discovery programs
  • Expertise in extending discovery research through translational human biology to clinical development, including biomarker development and in vitro human cellular assays
  • PhD in Immunology (or relevant field) and significant record of high quality publications and patents
  • 10 years or more experience in drug discovery programs in biotechnology and/or pharma companies
  • Excellent teaming skills and communication skills. Strong scientific presentation skills

Further Recruiting Information
For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job (113DK) to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.
 
 
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